Invitrogen

CD268 (BAFF Receptor) Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details

View all (21) BAFF Receptor (CD268) antibodies

Datasheet

Questions & Answers

Datasheet

Questions & Answers

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CD268 (BAFF Receptor) Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of CD268 (BAFF Receptor) in human tonsil and cerebral cortex tissues using a CD268 (BAFF Receptor) polyclonal antibody (Product # PA5-82071). Corresponding RNA-seq data are presented for the same tissues.

CD268 (BAFF Receptor) Antibody in Western Blot (WB) — Western blot analysis of CD268 (BAFF Receptor) by a CD268 (BAFF Receptor) polyclonal antibody (Product # PA5-82071). Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 Lane 2: Negative control (vector only transfected HEK293T lysate) Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY409380).

CD268 (BAFF Receptor) Antibody in Relative expression — Relative expression in different tissues in IHC: Detection of differential expression levels of CD268 (BAFF Receptor) demonstrates antibody specificity. Immunohistochemical analysis of CD268 (BAFF Receptor) using anti-CD268 (BAFF Receptor) Polyclonal Antibody (Product #PA5-82071), shows significant staining of CD268 (BAFF Receptor) in tonsil and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of CD268 (BAFF Receptor) within each tissue is shown using RNA-Seq. {RE}

Product Details

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Western Blot (WB)

0.04-0.4 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TNFRSF13C

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2789232

Product Specific Information

Immunogen sequence: SWRRRQRRLR GASSAEAPDG DKDAPEPLDK VIILSPGISD ATAPAWPPPG EDPGTTPPGH SVPVPATELG STELVTTKTA GPEQQ

Target Information

Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13. 1-q13. 31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B cell-activating factor receptor; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BAFFR; BLyS receptor 3; CD268; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C

Gene Aliases: BAFF-R; BAFFR; BR3; BROMIX; CD268; CVID4; prolixin; TNFRSF13C

UniProt ID: (Human) Q96RJ3

Entrez Gene ID: (Human) 115650

Function(s)

B cell homeostasis adaptive immune response positive regulation of germinal center formation positive regulation of B cell proliferation T cell costimulation B cell costimulation tumor necrosis factor-mediated signaling pathway positive regulation of T cell proliferation positive regulation of interferon-gamma biosynthetic process