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Proteintech
CD300LG Polyclonal Antibody
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Product Details
15426-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CD300LG Fusion Protein Ag8075 (24-332 aa encoded by BC025395)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EISGFEGDT VSLQCTYREE LRDHRKYWCR KGGILFSRCS GTIYAEEEGQ ETMKGRVSIR DSRQELSLIV TLWNLTLQDA GEYWCGVEKR GPDESLLISL FVFPGPCCPP SPSPTFQPLA TTRLQPKAKA QQTQPPGLTS PGLYPAATTA KQGKTGAEAP PLPGTSQYGH ERTSQYTGTS PHPATSPPAG SSRPPMQLNS TSAEDTSPAL SSGSSKPRVS IPMVRILAPV LVLLSLLSAA GLIAFCSHLL LWRKEAQQAT ETQRNEKFCL SRLTAEEKEA PSQAPEGDVI SMPPLHTSEE ELGFSKFVSA (24-332 aa encoded by BC025395)
Target Information
CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule-like family member g; CD300g; CD300g antigen; CLM-9; CLM9Trem4; CMRF35-like molecule 9; TREM-4; Triggering receptor expressed on myeloid cells 4
Gene Aliases: CD300LG; CLM-9; CLM9; NEPMUCIN; TREM-4; TREM4; UNQ422/PRO846
UniProt ID: (Human) Q6UXG3
Entrez Gene ID: (Human) 146894
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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