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Invitrogen
CD300a Polyclonal Antibody
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Product Details
PA5-113473
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
C. elegans,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CMRF35-like molecule 8 protein (18-180AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD300 antigen-like family member A; CD300a; CD300a antigen; CLM-8; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1/IRC2; IRp60; leukocyte membrane antigen; Leukocyte mono-Ig-like receptor 1; MAIR-1; Mast cell-derived paired immunoglobulin-like receptor 1; Mcipr1; Myeloid-associated immunoglobulin-like receptor 1; NK inhibitory receptor; NKRL; polymeric immunoglobulin receptor 4
Gene Aliases: B230315M08Rik; CD300A; CLM-8; Clm8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; HSPC083; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60; LMIR1; MAIR-I; MAIR-Ia; Mcpir1; MMAC8; Pigr4
UniProt ID: (Human) Q9UGN4, (Mouse) Q6SJQ0
Entrez Gene ID: (Human) 11314, (Mouse) 217303
immune system process
cell adhesion
signal transduction
negative regulation of B cell proliferation
positive regulation of phosphoprotein phosphatase activity
negative regulation of mast cell activation involved in immune response
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
negative regulation of fibroblast proliferation
regulation of immune response
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of activation of JAK2 kinase activity
negative regulation of eosinophil migration
serotonin secretion by mast cell
receptor-mediated endocytosis
negative regulation of serotonin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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