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Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: macrophage galactose N-acetyl-galactosamine specific lectin 2; macrophage galactose-type C-type lectin 2
Gene Aliases: CD301b
Entrez Gene ID: (Mouse) 216864
Molecular Function:
cell adhesion molecule
cytokine receptor
defense/immunity protein
immunoglobulin receptor superfamily
receptor
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