Product References
Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury.
The Journal of experimental medicine
He H,Yang W,Su N,Zhang C,Dai J,Han F,Singhal M,Bai W,Zhu X,Zhu J,Liu Z,Xia W,Liu X,Zhang C,Jiang K,Huang W,Chen D,Wang Z,He X,Kirchhoff F,Li Z,Liu C,Huan J,Wang X,Wei W,Wang J,Augustin HG,Hu J
MA3105 was used in Immunohistochemistry to demonstrate that impaired NO-sGC crosstalk in the vascular niche results in elevated vascular permeability, and pharmacological activation of this crosstalk represents a promising translational therapy for ALI.
Mon Feb 06 00:00:00 EST 2023
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection.
Biology direct
Santos-Coquillat A,Herreros-Pérez D,Samaniego R,González MI,Cussó L,Desco M,Salinas B
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunohistochemistry
Mon Nov 14 00:00:00 EST 2022
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection.
Biology direct
Santos-Coquillat A,Herreros-Pérez D,Samaniego R,González MI,Cussó L,Desco M,Salinas B
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunohistochemistry
Mon Nov 14 00:00:00 EST 2022
Targeting Anti-Angiogenic VEGF165b-VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models.
Cells
Kuppuswamy S,Annex BH,Ganta VC
MA3105 was used in Western Blot to demonstrate that VEGF165b inhibition induces VEGFR1-STAT3 activation, which does not require increased NO to induce therapeutic angiogenesis in Peripheral Artery Disease (PAD).
Sun Aug 28 00:00:00 EDT 2022
Imaging Blood Vessels and Lymphatics in Mouse Trachea Wholemounts.
Methods in molecular biology (Clifton, N.J.)
Baluk P,McDonald DM
MA3105 was used in Flow Cytometry, Neutralization, Immunohistochemistry to describe practical immunohistochemical methods for fluorescence and confocal microscopy of wholemounts of the mouse trachea to achieve this purpose in which the entire vasculature can be visualized from the organ level to the cellular and subcellular level.
Thu Mar 31 00:00:00 EDT 2022
Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress.
Oncoimmunology
Cedervall J,Herre M,Dragomir A,Rabelo-Melo F,Svensson A,Thålin C,Rosell A,Hjalmar V,Wallén H,Lindman H,Pejler G,Hagström E,Hultström M,Larsson A,Olsson AK
MA3105 was used in Flow Cytometry, Neutralization, Immunohistochemistry to suggest NETs as potential therapeutic targets to prevent cardiac inflammation and dysfunction in cancer patients.
Fri Apr 08 00:00:00 EDT 2022
Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation.
Frontiers in immunology
Roy T,Banang-Mbeumi S,Boateng ST,Ruiz EM,Chamcheu RN,Kang L,King JA,Walker AL,Nagalo BM,Kousoulas KG,Esnault S,Huang S,Chamcheu JC
MA3105 was used in Immunohistochemistry (Paraffin) to suggest fisetin as a potential treatment for psoriasis and possibly other inflammatory skin diseases.
Tue Feb 07 00:00:00 EST 2023
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Hepatology (Baltimore, Md.)
Yang W,He H,Wang T,Su N,Zhang F,Jiang K,Zhu J,Zhang C,Niu K,Wang L,Yuan X,Liu N,Li L,Wei W,Hu J
MA3105 was used in Immunohistochemistry (Paraffin) to to provide a transcriptional roadmap for the activation of HSCs during liver fibrosis and yields comprehensive evidence that the differential transcriptomic features of HSCs and PFs, along with their relative contributions to liver fibrosis of different etiologies, should be considered in developing effective anti-fibrotic therapeutic strategies.
Mon Nov 01 00:00:00 EDT 2021
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Hepatology (Baltimore, Md.)
Yang W,He H,Wang T,Su N,Zhang F,Jiang K,Zhu J,Zhang C,Niu K,Wang L,Yuan X,Liu N,Li L,Wei W,Hu J
MA3105 was used in Immunohistochemistry (Paraffin) to to provide a transcriptional roadmap for the activation of HSCs during liver fibrosis and yields comprehensive evidence that the differential transcriptomic features of HSCs and PFs, along with their relative contributions to liver fibrosis of different etiologies, should be considered in developing effective anti-fibrotic therapeutic strategies.
Mon Nov 01 00:00:00 EDT 2021
Dual role for CXCL12 signaling in semilunar valve development.
Cell reports
Ridge LA,Kewbank D,Schütz D,Stumm R,Scambler PJ,Ivins S
MA3105 was used in Immunohistochemistry to investigate if CXCL12 signaling via its receptor CXCR4 fulfills distinct roles at different stages of semilunar valves development.
Tue Aug 24 00:00:00 EDT 2021
Dual role for CXCL12 signaling in semilunar valve development.
Cell reports
Ridge LA,Kewbank D,Schütz D,Stumm R,Scambler PJ,Ivins S
MA3105 was used in Immunohistochemistry to investigate if CXCL12 signaling via its receptor CXCR4 fulfills distinct roles at different stages of semilunar valves development.
Tue Aug 24 00:00:00 EDT 2021
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
Nature communications
Aneas I,Decker DC,Howard CL,Sobreira DR,Sakabe NJ,Blaine KM,Stein MM,Hrusch CL,Montefiori LE,Tena J,Magnaye KM,Clay SM,Gern JE,Jackson DJ,Altman MC,Naureckas ET,Hogarth DK,White SR,Gomez-Skarmeta JL,Schoetler N,Ober C,Sperling AI,Nóbrega MA
MA3105 was used in immunohistochemistry (frozen) to identify a 5 kb region within the GWAS-defined segment that acts as an enhancer-blocking element in vivo and in vitro.
Thu Oct 21 00:00:00 EDT 2021
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
Nature communications
Aneas I,Decker DC,Howard CL,Sobreira DR,Sakabe NJ,Blaine KM,Stein MM,Hrusch CL,Montefiori LE,Tena J,Magnaye KM,Clay SM,Gern JE,Jackson DJ,Altman MC,Naureckas ET,Hogarth DK,White SR,Gomez-Skarmeta JL,Schoetler N,Ober C,Sperling AI,Nóbrega MA
MA3105 was used in immunohistochemistry (frozen) to identify a 5 kb region within the GWAS-defined segment that acts as an enhancer-blocking element in vivo and in vitro.
Thu Oct 21 00:00:00 EDT 2021
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
MA3105 was used in Immunohistofluorescence to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
MA3105 was used in Immunohistofluorescence to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury.
The American journal of pathology
Baluk P,Naikawadi RP,Kim S,Rodriguez F,Choi D,Hong YK,Wolters PJ,McDonald DM
MA3105 was used in Immunohistochemistry to suggest that lymphatics have an overall protective effect in lung injury and fibrosis and fit with a mechanism whereby lung lymphatic network expansion reduces lymph stasis and increases clearance of fluid and cells, including profibrotic macrophages.
Tue Dec 01 00:00:00 EST 2020
An Integrated Transcriptome Analysis Reveals IGFBP7 Upregulation in Vasculature in Traumatic Brain Injury.
Frontiers in genetics
Wang J,Deng X,Xie Y,Tang J,Zhou Z,Yang F,He Q,Cao Q,Zhang L,He L
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunohistochemistry
Sat Jan 30 00:00:00 EST 2021
A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression.
Cell death & disease
Dai J,Zhang C,Guo L,He H,Jiang K,Huang Y,Zhang X,Zhang H,Wei W,Zhang Y,Lu L,Hu J
MA3105 was used in Immunocytochemistry-Immunofluorescence to identify, during acute inflammation, mixed-lineage kinase domain-like protein can regulate endothelial adhesion molecule expression and local EC-leukocyte interaction.
Fri Apr 24 00:00:00 EDT 2020
A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression.
Cell death & disease
Dai J,Zhang C,Guo L,He H,Jiang K,Huang Y,Zhang X,Zhang H,Wei W,Zhang Y,Lu L,Hu J
MA3105 was used in Immunocytochemistry-Immunofluorescence to identify, during acute inflammation, mixed-lineage kinase domain-like protein can regulate endothelial adhesion molecule expression and local EC-leukocyte interaction.
Fri Apr 24 00:00:00 EDT 2020
Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.
EMBO reports
Testini C,Smith RO,Jin Y,Martinsson P,Sun Y,Hedlund M,Sáinz-Jaspeado M,Shibuya M,Hellström M,Claesson-Welsh L
MA3105 was used in Immunohistochemistry to show vascular endothelial growth factor receptor-2 phosphotyrosine 1212 signalling activates ERK1/2 and Akt pathways for endothelial proliferation mediated by c-Myc.
Tue Nov 05 00:00:00 EST 2019
Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.
Cell reports
Coulombe P,Paliouras GN,Clayton A,Hussainkhel A,Fuller M,Jovanovic V,Dauphinee S,Umlandt P,Xiang P,Kyle AH,Minchinton AI,Humphries RK,Hoodless PA,Parker JDK,Wright JL,Karsan A
MA3105 was used in Flow cytometry/Cell sorting to determine the functional mechanism of Sash1 in lung maturation during embryonic development.
Tue May 07 00:00:00 EDT 2019
Beneficial effects of sunitinib on tumor microenvironment and immunotherapy targeting death receptor5.
Oncoimmunology
Tsukita Y,Okazaki T,Ebihara S,Komatsu R,Nihei M,Kobayashi M,Hirano T,Sugiura H,Tamada T,Tanaka N,Sato Y,Yagita H,Ichinose M
MA3105 was used in Immunohistochemistry to investigate the effects of a simultaneous functional improvement of abnormal blood vessels and lymphatics on the immune microenvironment.
Tue Jan 12 00:00:00 EST 2021
Left pulmonary artery in 22q11.2 deletion syndrome. Echocardiographic evaluation in patients without cardiac defects and role of Tbx1 in mice.
PloS one
Mastromoro G,Calcagni G,Versacci P,Putotto C,Chinali M,Lambiase C,Unolt M,Pelliccione E,Anaclerio S,Caprio C,Cioffi S,Bilio M,Baban A,Drago F,Digilio MC,Marino B,Baldini A
MA3105 was used in Immunohistochemistry-immunofluorescence to study the expression of Tbx1 in the morphogenesis of pulmonary arteries.
Tue Dec 31 00:00:00 EST 2019
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.
The Journal of clinical investigation
Lugano R,Vemuri K,Yu D,Bergqvist M,Smits A,Essand M,Johansson S,Dejana E,Dimberg A
MA3105 was used in Immunohistochemistry-immunofluorescence to demonstrate that CD93 regulates Β1 integrin signalling and organisation of fibronectin fibrillogenesis during tumour vascularisation.
Wed Aug 01 00:00:00 EDT 2018
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.
The Journal of clinical investigation
Lugano R,Vemuri K,Yu D,Bergqvist M,Smits A,Essand M,Johansson S,Dejana E,Dimberg A
MA3105 was used in Immunohistochemistry-immunofluorescence to demonstrate that CD93 regulates Β1 integrin signalling and organisation of fibronectin fibrillogenesis during tumour vascularisation.
Wed Aug 01 00:00:00 EDT 2018
CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.
The Journal of clinical investigation
Lugano R,Vemuri K,Yu D,Bergqvist M,Smits A,Essand M,Johansson S,Dejana E,Dimberg A
MA3105 was used in Immunohistochemistry-immunofluorescence to demonstrate that CD93 regulates Β1 integrin signalling and organisation of fibronectin fibrillogenesis during tumour vascularisation.
Wed Aug 01 00:00:00 EDT 2018
Endothelial cell fitness dictates the source of regenerating liver vasculature.
The Journal of experimental medicine
Singhal M,Liu X,Inverso D,Jiang K,Dai J,He H,Bartels S,Li W,Abdul Pari AA,Gengenbacher N,Besemfelder E,Hui L,Augustin HG,Hu J
MA3105 was used in Immunohistochemistry-immunofluorescence to reconcile many of the discrepancies in the literature and highlight that the cellular source of regenerating endothelium depends on the fitness of the residual vasculature.
Mon Oct 01 00:00:00 EDT 2018
Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1).
Scientific reports
Oladipupo SS,Kabir AU,Smith C,Choi K,Ornitz DM
MA3105 was used in Immunohistochemistry-immunofluorescence to investigate gene dosage effects of Vegfr2, Fgfr1, and Fgfr2 in three independent mouse models of tumourigenesis.
Wed Oct 03 00:00:00 EDT 2018
Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1).
Scientific reports
Oladipupo SS,Kabir AU,Smith C,Choi K,Ornitz DM
MA3105 was used in Immunohistochemistry-immunofluorescence to investigate gene dosage effects of Vegfr2, Fgfr1, and Fgfr2 in three independent mouse models of tumourigenesis.
Wed Oct 03 00:00:00 EDT 2018
Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis.
JCI insight
Kabir AU,Lee TJ,Pan H,Berry JC,Krchma K,Wu J,Liu F,Kang HK,Hinman K,Yang L,Hamilton S,Zhou Q,Veis DJ,Mecham RP,Wickline SA,Miller MJ,Choi K
MA3105 was used in Immunohistochemistry on frozen tissues to characterise the expression of Etv2 in both human and mouse tumour-associated endothelial cells, and elucidate its role in tumour angiogenesis.
Thu Apr 19 00:00:00 EDT 2018
Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis.
JCI insight
Kabir AU,Lee TJ,Pan H,Berry JC,Krchma K,Wu J,Liu F,Kang HK,Hinman K,Yang L,Hamilton S,Zhou Q,Veis DJ,Mecham RP,Wickline SA,Miller MJ,Choi K
MA3105 was used in Immunohistochemistry on frozen tissues to characterise the expression of Etv2 in both human and mouse tumour-associated endothelial cells, and elucidate its role in tumour angiogenesis.
Thu Apr 19 00:00:00 EDT 2018
Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.
Nature communications
Stremmel C,Schuchert R,Wagner F,Thaler R,Weinberger T,Pick R,Mass E,Ishikawa-Ankerhold HC,Margraf A,Hutter S,Vagnozzi R,Klapproth S,Frampton J,Yona S,Scheiermann C,Molkentin JD,Jeschke U,Moser M,Sperandio M,Massberg S,Geissmann F,Schulz C
MA3105 was used in Flow cytometry/Cell sorting to close an important gap in our understanding of the development of the innate immune system.
Mon Jan 08 00:00:00 EST 2018
Tumor endothelial marker 8 promotes cancer progression and metastasis.
Oncotarget
Høye AM,Tolstrup SD,Horton ER,Nicolau M,Frost H,Woo JH,Mauldin JP,Frankel AE,Cox TR,Erler JT
MA3105 was used in Immunohistochemistry to show that the loss of Tumour Endothelial Marker 8 results in inhibition of cancer progression, reduction in tumour angiogenesis and reduced metastatic burden in breast cancer mouse models.
Tue Jul 10 00:00:00 EDT 2018
Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.
Cancer cell
Seaman S,Zhu Z,Saha S,Zhang XM,Yang MY,Hilton MB,Morris K,Szot C,Morris H,Swing DA,Tessarollo L,Smith SW,Degrado S,Borkin D,Jain N,Scheiermann J,Feng Y,Wang Y,Li J,Welsch D,DeCrescenzo G,Chaudhary A,Zudaire E,Klarmann KD,Keller JR,Dimitrov DS,St Croix B
MA3105 was used in Flow cytometry/Cell sorting to demonstrate that the cell surface protein CD276/B7-H3 is broadly over-expressed by multiple tumour types on both cancer cells and tumour-infiltrating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
Mon Apr 10 00:00:00 EDT 2017
Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.
Cancer cell
Seaman S,Zhu Z,Saha S,Zhang XM,Yang MY,Hilton MB,Morris K,Szot C,Morris H,Swing DA,Tessarollo L,Smith SW,Degrado S,Borkin D,Jain N,Scheiermann J,Feng Y,Wang Y,Li J,Welsch D,DeCrescenzo G,Chaudhary A,Zudaire E,Klarmann KD,Keller JR,Dimitrov DS,St Croix B
MA3105 was used in Flow cytometry/Cell sorting to demonstrate that the cell surface protein CD276/B7-H3 is broadly over-expressed by multiple tumour types on both cancer cells and tumour-infiltrating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
Mon Apr 10 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunohistochemistry
Wed Mar 01 00:00:00 EST 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunohistochemistry
Wed Mar 01 00:00:00 EST 2017
3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.
JCI insight
Surolia R,Li FJ,Wang Z,Li H,Liu G,Zhou Y,Luckhardt T,Bae S,Liu RM,Rangarajan S,de Andrade J,Thannickal VJ,Antony VB
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunofluorescence
Thu Jan 26 00:00:00 EST 2017
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
The Journal of clinical investigation
Kim M,Allen B,Korhonen EA,Nitschké M,Yang HW,Baluk P,Saharinen P,Alitalo K,Daly C,Thurston G,McDonald DM
Thu Sep 01 00:00:00 EDT 2016
Loss of endogenous thymosin β4 accelerates glomerular disease.
Kidney international
Vasilopoulou E,Kolatsi-Joannou M,Lindenmeyer MT,White KE,Robson MG,Cohen CD,Sebire NJ,Riley PR,Winyard PJ,Long DA
MA3105 was used in immunohistochemistry - paraffin section to determine the function of thymosin in the kidneys
Tue Nov 01 00:00:00 EDT 2016
Loss of endogenous thymosin β4 accelerates glomerular disease.
Kidney international
Vasilopoulou E,Kolatsi-Joannou M,Lindenmeyer MT,White KE,Robson MG,Cohen CD,Sebire NJ,Riley PR,Winyard PJ,Long DA
MA3105 was used in immunohistochemistry - paraffin section to determine the function of thymosin in the kidneys
Tue Nov 01 00:00:00 EDT 2016
Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases.
Journal of the American Society of Nephrology : JASN
Huang JL,Woolf AS,Kolatsi-Joannou M,Baluk P,Sandford RN,Peters DJ,McDonald DM,Price KL,Winyard PJ,Long DA
MA3105 was used in immunohistochemistry - frozen section to find that cystogenesis is associated with a disorganized pericystic network of vessels expressing platelet/endothelial cell adhesion molecule 1 and vascular endothelial growth factor receptor 3
Fri Jan 01 00:00:00 EST 2016
Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors.
Clinical & experimental metastasis
Moen I,Gebre M,Alonso-Camino V,Chen D,Epstein D,McDonald DM
MA3105 was used in immunohistochemistry (frozen) to characterize the anti-tumor effects of OXA-11.
Tue Dec 01 00:00:00 EST 2015
NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization.
Oncoimmunology
Yotsumoto F,You WK,Cejudo-Martin P,Kucharova K,Sakimura K,Stallcup WB
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunofluorescence
Wed Apr 01 00:00:00 EDT 2015
NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization.
Oncoimmunology
Yotsumoto F,You WK,Cejudo-Martin P,Kucharova K,Sakimura K,Stallcup WB
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunofluorescence
Wed Apr 01 00:00:00 EDT 2015
Preferential lymphatic growth in bronchus-associated lymphoid tissue in sustained lung inflammation.
The American journal of pathology
Baluk P,Adams A,Phillips K,Feng J,Hong YK,Brown MB,McDonald DM
Thu May 01 00:00:00 EDT 2014
Neutrophil dependence of vascular remodeling after Mycoplasma infection of mouse airways.
The American journal of pathology
Baluk P,Phillips K,Yao LC,Adams A,Nitschké M,McDonald DM
MA3105 was used in immunohistochemistry to investigate the role of neutrophil during vascular remodeling after Mycoplasma infection of mouse airways
Sun Jun 01 00:00:00 EDT 2014
Transgenic overexpression of interleukin-1β induces persistent lymphangiogenesis but not angiogenesis in mouse airways.
The American journal of pathology
Baluk P,Hogmalm A,Bry M,Alitalo K,Bry K,McDonald DM
Published figure using CD31 monoclonal antibody (Product # MA3105) in Immunofluorescence
Mon Apr 01 00:00:00 EDT 2013
An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo.
PloS one
Majima T,Takeuchi K,Sano K,Hirashima M,Zankov DP,Tanaka-Okamoto M,Ishizaki H,Miyoshi J,Ogita H
MA3105 was used in immunohistochemistry to study the role of RhoA in the mechanism by which afadin modulates murine embryo lymphangiogenesis
Tue Oct 10 00:00:00 EDT 2017
Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy.
American journal of respiratory and critical care medicine
Nakanishi K,Takeda Y,Tetsumoto S,Iwasaki T,Tsujino K,Kuhara H,Jin Y,Nagatomo I,Kida H,Goya S,Kijima T,Maeda N,Funahashi T,Shimomura I,Tachibana I,Kawase I
MA3105 was used in immunocytochemistry to study the COPD-like phenotype in adiponectin-null mice.
Sun May 01 00:00:00 EDT 2011
Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B.
The American journal of pathology
Falcon BL,Pietras K,Chou J,Chen D,Sennino B,Hanahan D,McDonald DM
MA3105 was used in immunohistochemistry to study the ability of PDBF-B inhibition to increase the venous delivery and chemotherapeutic efficacy of cyclophosphoramide
Wed Jun 01 00:00:00 EDT 2011
Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.
The American journal of pathology
Fuxe J,Tabruyn S,Colton K,Zaid H,Adams A,Baluk P,Lashnits E,Morisada T,Le T,O'Brien S,Epstein DM,Koh GY,McDonald DM
MA3105 was used in Immunohistochemistry to show that pericyte contributions to endothelial stability have greater dependence on PDGF-B during the development of sustained inflammation than under baseline conditions or in acute inflammation.
Wed Jun 01 00:00:00 EDT 2011
IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
Journal of immunology (Baltimore, Md. : 1950)
Turnquist HR,Zhao Z,Rosborough BR,Liu Q,Castellaneta A,Isse K,Wang Z,Lang M,Stolz DB,Zheng XX,Demetris AJ,Liew FY,Wood KJ,Thomson AW
MA3105 was used in immunohistochemistry to study the effect of IL-33 on suppressive CD11b+ Gr-1 int and regulatory T cells and its role in cardiac allograft survival
Tue Nov 01 00:00:00 EDT 2011
Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.
Cancer research
Hashizume H,Falcón BL,Kuroda T,Baluk P,Coxon A,Yu D,Bready JV,Oliner JD,McDonald DM
MA3105 was used in immunohistochemistry to study the complimentary effects of concurrent inhibition of angiopoietin-2 and VEGF on tumour growth in a human colon carcinoma mouse xenofraft model
Mon Mar 15 00:00:00 EDT 2010
Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody.
Molecular cancer therapeutics
Coxon A,Bready J,Min H,Kaufman S,Leal J,Yu D,Lee TA,Sun JR,Estrada J,Bolon B,McCabe J,Wang L,Rex K,Caenepeel S,Hughes P,Cordover D,Kim H,Han SJ,Michaels ML,Hsu E,Shimamoto G,Cattley R,Hurh E,Nguyen L,Wang SX,Ndifor A,Hayward IJ,Falcón BL,McDonald DM,Li L,Boone T,Kendall R,Radinsky R,Oliner JD
MA3105 was used in immunohistochemistry to study the effect of inhibition of angiotensin-1 on angiogenesis and tumor growth and the significance for a novel peptide-Fc fusion dual angiotensin1/2 inhibitor
Fri Oct 01 00:00:00 EDT 2010
Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways.
The American journal of pathology
Yao LC,Baluk P,Feng J,McDonald DM
MA3105 was used in immunohistochemistry to investigate the reversibility of lymphatic remodeling in chronically inflamed airways
Mon Mar 01 00:00:00 EST 2010
Rapid remodeling of airway vascular architecture at birth.
Developmental dynamics : an official publication of the American Association of Anatomists
Ni A,Lashnits E,Yao LC,Baluk P,McDonald DM
MA3105 was used in immunohistochemistry to investigate the plasticity of airway vasculature
Wed Sep 01 00:00:00 EDT 2010
TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice.
The Journal of clinical investigation
Baluk P,Yao LC,Feng J,Romano T,Jung SS,Schreiter JL,Yan L,Shealy DJ,McDonald DM
MA3105 was used in immunohistochemistry to determine the role of TNF-alpha in vessel remodeling in murine sustained airway inflammation
Thu Oct 01 00:00:00 EDT 2009
Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice.
The American journal of pathology
Okazaki T,Ni A,Baluk P,Ayeni OA,Kearley J,Coyle AJ,Humbles A,McDonald DM
MA3105 was used in immunohistochemistry to investigate the influence of EphA2 deficiency on blood vessel development and inflammatory response
Mon Jun 01 00:00:00 EDT 2009
Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.
The American journal of pathology
Falcón BL,Hashizume H,Koumoutsakos P,Chou J,Bready JV,Coxon A,Oliner JD,McDonald DM
MA3105 was used in Immunohistochemistry to study how inhibition of Ang2 leads to normalization of tumor blood vessels by permitting the unopposed action of Ang1, but decreases tumor vascularity primarily by blocking Ang2 actions.
Sun Nov 01 00:00:00 EDT 2009
alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation.
The American journal of pathology
Okazaki T,Ni A,Ayeni OA,Baluk P,Yao LC,Vossmeyer D,Zischinsky G,Zahn G,Knolle J,Christner C,McDonald DM
MA3105 was used in immunohistochemistry to investigate the effect of alpha 5 beta 1 integrin blockade on lymphangiogenesis during inflammation
Mon Jun 01 00:00:00 EDT 2009
Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.
Biochemical and biophysical research communications
Kanemura H,Satoh T,Bilasy SE,Ueda S,Hirashima M,Kataoka T
MA3105 was used in immunohistochemistry to study the role of RA-GEF-1 in the vascular development
Fri Oct 02 00:00:00 EDT 2009
Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos.
Developmental biology
Hirashima M,Sano K,Morisada T,Murakami K,Rossant J,Suda T
MA3105 was used in ELISA to investigate the role of lymphatic vessel assembly
Tue Apr 01 00:00:00 EDT 2008
Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils.
Arthritis and rheumatism
Filer A,Parsonage G,Smith E,Osborne C,Thomas AM,Curnow SJ,Rainger GE,Raza K,Nash GB,Lord J,Salmon M,Buckley CD
MA3105 was used in immunohistochemistry to study the effect of fibroblasts on leukocyte survival
Sat Jul 01 00:00:00 EDT 2006
Role of PECAM-1 (CD31) in neutrophil transmigration in murine models of liver and peritoneal inflammation.
The American journal of physiology
Chosay JG,Fisher MA,Farhood A,Ready KA,Dunn CJ,Jaeschke H
MA3105 was used in blocking/activating experiment to assess the function of platelet endothelial cell adhesion molecule-1 in neutrophil migration
Wed Apr 01 00:00:00 EST 1998