This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
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Protein Aliases: CD32; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIB; Fc gamma RIIB; Fc receptor, IgG, low affinity IIb; FC-gamma RII; Fc-gamma RII-b; Fc-gamma-RII; Fc-gamma-RIIb; FCG2; Fcgamma RIIc; Fcgamma-RIIc; FcgammaRIIB; FCGR2C; FcRII; fcRII-b; FcRII-c; IGFR2; IgG Fc receptor II beta; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; Lymphocyte antigen 17
Gene Aliases: AI528646; CD32; CD32B; F630109E10Rik; Fc[g]RII; FCG2; FcgammaRIIB2; FCGR2; Fcgr2a; FCGR2B; FcgRII; Fcr-2; Fcr-3; FCRII; IGFR2; Ly-17; Ly-m20; LyM-1
Molecular Function: cell adhesion molecule