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          • Primary Antibodies ›
          • CD36 Antibodies

          Invitrogen

          CD36 Polyclonal Antibody

          View all (102) CD36 antibodies

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          Cite CD36 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          CD36 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          CD36 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          CD36 Antibody (PA5-89991) in WB

          Western blot analysis of CD36 in various lysates. Samples were incubated with CD36 Polyclonal antibody (Product # PA5-89991) using a dilution of 1:400, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD36 Antibody in Western Blot (WB)
          CD36 Antibody in Western Blot (WB)

          Product Details

          PA5-89991

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein (or fragment).

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.57 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2805879

          Product Specific Information

          Positive Samples: HeLa, 293T, Mouse heart, Rat heart; Cellular Location: Cell membrane, Multi-pass membrane protein

          Target Information

          CD36, also known as scavenger receptor class B member 3, is a protein that is expressed on the surface of various cell types, including macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and is involved in the recognition and uptake of various ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells. CD36 is also implicated in the pathogenesis of malaria. The protein encoded by this gene serves as a receptor for thrombospondin in platelets and various cell lines, and is the fourth major glycoprotein of the platelet surface. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL, and directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: 85 kda protein; 88 kda cell surface glycoprotein; adipocyte membrane protein; CD36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (CD36 blood group) transcript; CD36 molecule (thrombospondin receptor); CD36 molecule (thrombospondin receptor) isoform CD36_1; CD36 molecule (thrombospondin receptor) isoform CD36_2; CD36 molecule (thrombospondin receptor) isoform CD36_3; cluster determinant 36; collagen type I receptor thrombospondin receptor; FAT; Fatty acid translocase; fatty acid transport protein; glycoprotein GPIIIb/GPIV; Glycoprotein IIIb; GPIIIB; GPIV; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; PAS-4 protein; Platelet collagen receptor; Platelet glycoprotein 4; Platelet glycoprotein IV; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor; unnamed protein product

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          Gene Aliases: BDPLT10; CD36; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3

          View more View less

          UniProt ID: (Human) P16671, (Mouse) Q08857

          View more View less

          Entrez Gene ID: (Human) 948, (Rat) 29184, (Mouse) 12491

          View more View less

          Function(s)
          beta-amyloid binding low-density lipoprotein receptor activity scavenger receptor activity long-chain fatty acid transporter activity protein binding high-density lipoprotein particle binding lipid binding short-chain fatty acid uptake transporter activity low-density lipoprotein particle binding Toll-like receptor binding cargo receptor activity macromolecular complex binding transforming growth factor beta binding thrombospondin receptor activity lipoteichoic acid receptor activity lipoprotein particle binding oxidised low-density lipoprotein particle receptor activity oleate transmembrane transporter activity oleic acid binding membrane trafficking regulatory protein
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter MAPK cascade positive regulation of cell-matrix adhesion production of molecular mediator involved in inflammatory response lipid metabolic process fatty acid metabolic process lipid transport receptor-mediated endocytosis phagocytosis, recognition phagocytosis, engulfment cell adhesion cell surface receptor signaling pathway positive regulation of cytosolic calcium ion concentration blood coagulation response to bacterium positive regulation of gene expression negative regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of cholesterol storage fatty acid transport long-chain fatty acid transport plasma membrane long-chain fatty acid transport short-chain fatty acid transport negative regulation of angiogenesis lipid storage cGMP-mediated signaling positive regulation of blood coagulation intestinal cholesterol absorption cholesterol transport receptor internalization regulation of lipopolysaccharide-mediated signaling pathway positive regulation of interleukin-1 beta production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production response to lipid regulation of toll-like receptor signaling pathway triglyceride transport plasma lipoprotein particle clearance low-density lipoprotein particle clearance cellular response to oxidative stress response to stilbenoid nitric oxide-cGMP-mediated signaling pathway negative regulation of protein import into nucleus lipoprotein transport positive regulation of I-kappaB kinase/NF-kappaB signaling regulation of protein complex assembly apoptotic cell clearance positive regulation of MAPK cascade long-chain fatty acid import positive regulation of nitric oxide biosynthetic process positive regulation of angiogenesis defense response to Gram-positive bacterium intestinal absorption sensory perception of taste low-density lipoprotein particle mediated signaling positive regulation of phagocytosis, engulfment positive regulation of macrophage cytokine production positive regulation of ERK1 and ERK2 cascade cholesterol import response to fatty acid response to linoleic acid cellular response to bacterial lipopeptide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to low-density lipoprotein particle stimulus cellular response to hydroperoxide cellular response to diacyl bacterial lipopeptide energy homeostasis regulation of action potential positive regulation of cold-induced thermogenesis cellular response to oxidised low-density lipoprotein particle stimulus oxidised low-density lipoprotein particle clearance amyloid-beta clearance by cellular catabolic process positive regulation of NLRP3 inflammasome complex assembly positive regulation of protein localization to plasma membrane positive regulation of reactive oxygen species biosynthetic process cellular response to beta-amyloid amyloid fibril formation lipid transport across blood brain barrier regulation of removal of superoxide radicals positive regulation of blood microparticle formation positive regulation of reactive oxygen species metabolic process long-chain fatty acid metabolic process pattern recognition receptor signaling pathway negative regulation of systemic arterial blood pressure triglyceride metabolic process signal transduction nitric oxide mediated signal transduction response to nutrient response to mechanical stimulus response to activity fatty acid oxidation response to estradiol cellular response to insulin stimulus response to drug negative regulation of transcription factor import into nucleus negative regulation of growth of symbiont in host digestive tract development positive regulation of cytokine secretion positive regulation of peptidyl-tyrosine phosphorylation response to growth hormone transport regulation of transcription from RNA polymerase II promoter in response to oxidative stress
          It has to be done as per old AB suggested Products section.

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