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Invitrogen
CD3e/CD8 Antibody Cocktail, FITC, PE
Product Details
MA5-16606
Product Specifications
Species Reactivity
Dog
Host/Isotype
Mixed
/ IgG1
Class
Cocktail
Type
Antibody
Clone
CA17.2A12/YCATE55.9
Immunogen
Affinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-9, Canine CD8 alpha chimaeric human IgG1 Fc fusion protein.
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Purification
purified
Storage buffer
PBS with 1% BSA, 5% sucrose
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538105
Product Specific Information
This antibody recognizes canine CD3 epsilon and CD8 cell surface antigens. Clone CA17.2A12 is a FITC-conjugated mouse IgG1 that recognizes canine CD3, a T cell differentiation antigen expressed on mature T lymphocytes. Clone YCATE 55.9 is an RPE-conjugated Rat IgG1 that recognizes canine CD8 epsilon, which is expressed by cytotoxic T cells. YCATE 55.9 binds to CD8 alpha.
Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Target Information
putative component of the CD3 T-cell receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD3 epsilon; CD3d molecule, delta (CD3-TCR complex); CD3E antigen, epsilon polypeptide (TiT3 complex); CD3g molecule, gamma (CD3-TCR complex); CD8 antigen, alpha polypeptide (p32); CD8a; CD8alpha; CD8beta; FLJ18683; Leu-2; T-cell surface glycoprotein CD8 alpha chain
Gene Aliases: CD8A
UniProt ID: (Dog) P33706
Entrez Gene ID: (Dog) 479419, (Dog) 442981, (Dog) 489383, (Dog) 403157, (Dog) 483076
positive regulation of cell-matrix adhesion
adaptive immune response
positive regulation of T cell anergy
negative regulation of gene expression
dendrite development
cerebellum development
T cell costimulation
positive regulation of interferon-gamma production
positive regulation of interleukin-4 production
positive regulation of cell-cell adhesion mediated by integrin
negative thymic T cell selection
negative regulation of smoothened signaling pathway
positive regulation of alpha-beta T cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway
apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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