PA5-29387 targets CD3 gamma in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29387 immunogen is synthetic peptide corresponding to a region within amino acids 106 and 182 of Human CD3 gamma.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
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Protein Aliases: CD3-GAMMA; CD3g; CD3g antigen; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); epsilon CD3-TCR complex; gamma polypeptide TiT3 complex; gamma subunit of T3; T-cell antigen receptor complex; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain; T3G
Gene Aliases: CD3-GAMMA; CD3G; IMD17; T3G
UniProt ID: (Human) P09693
Entrez Gene ID: (Human) 917