Product References
HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization.
Molecular cell
Wei X,Xiang Y,Peters DT,Marius C,Sun T,Shan R,Ou J,Lin X,Yue F,Li W,Southerland KW,Diao Y
MHCD4520 was used in Flow cytometry/Cell sorting to find that the poised" gene promoters exhibit silencer-like function to repress the expression of distal genes via promoter-promoter interactions."
Thu Mar 17 00:00:00 EDT 2022
Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.
Cell metabolism
Benjamin DI,Both P,Benjamin JS,Nutter CW,Tan JH,Kang J,Machado LA,Klein JDD,de Morree A,Kim S,Liu L,Dulay H,Feraboli L,Louie SM,Nomura DK,Rando TA
MHCD4520 was used in Flow cytometry/Cell sorting to report that fasting slows muscle repair both immediately after the conclusion of fasting as well as after multiple days of refeeding.
Tue Jun 07 00:00:00 EDT 2022
Tracking the expression of therapeutic protein targets in rare cells by antibody-mediated nanoparticle labelling and magnetic sorting.
Nature biomedical engineering
Labib M,Wang Z,Ahmed SU,Mohamadi RM,Duong B,Green B,Sargent EH,Kelley SO
MHCD4520 was used in Immunocytochemistry to show that mutated proteins that are drug targets or markers of therapeutic response can be directly identified in CTCs, analysed at the single-cell level and used to predict how mice with drug-susceptible and drug-resistant pancreatic tumour xenografts respond to therapy.
Fri Jan 01 00:00:00 EST 2021
ALICE: a hybrid AI paradigm with enhanced connectivity and cybersecurity for a serendipitous encounter with circulating hybrid cells.
Theranostics
Cheng KS,Pan R,Pan H,Li B,Meena SS,Xing H,Ng YJ,Qin K,Liao X,Kosgei BK,Wang Z,Han RPS
MHCD4520 was used in Immunocytochemistry to present a machine-learning-augmented rule-based hybrid AI algorithm with enhanced cybersecurity and connectivity for the automatic and flexibly-adapting enumeration of cellular liquid biopsies.
Mon May 31 00:00:00 EDT 2021
ALICE: a hybrid AI paradigm with enhanced connectivity and cybersecurity for a serendipitous encounter with circulating hybrid cells.
Theranostics
Cheng KS,Pan R,Pan H,Li B,Meena SS,Xing H,Ng YJ,Qin K,Liao X,Kosgei BK,Wang Z,Han RPS
MHCD4520 was used in Immunocytochemistry to present a machine-learning-augmented rule-based hybrid AI algorithm with enhanced cybersecurity and connectivity for the automatic and flexibly-adapting enumeration of cellular liquid biopsies.
Mon May 31 00:00:00 EDT 2021
Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.
Nature communications
Sarkar TJ,Quarta M,Mukherjee S,Colville A,Paine P,Doan L,Tran CM,Chu CR,Horvath S,Qi LS,Bhutani N,Rando TA,Sebastiano V
Published figure using CD45 monoclonal antibody (Product # MHCD4520) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Mitochondrial Transfer of Wharton's Jelly Mesenchymal Stem Cells Eliminates Mutation Burden and Rescues Mitochondrial Bioenergetics in Rotenone-Stressed MELAS Fibroblasts.
Oxidative medicine and cellular longevity
Lin TK,Chen SD,Chuang YC,Lan MY,Chuang JH,Wang PW,Hsu TY,Wang FS,Tsai MH,Huang ST,Wang XW,Tsai PC,Lin HY,Liou CW
MHCD4520 was used in Flow cytometry/Cell sorting to determine the therapeutic effect of Wharton's jelly mesenchymal stem cells on mitochondiral dysfunction in MELAS patients.
Fri Dec 13 00:00:00 EST 2019
CTC phenotyping for a preoperative assessment of tumor metastasis and overall survival of pancreatic ductal adenocarcinoma patients.
EBioMedicine
Sun Y,Wu G,Cheng KS,Chen A,Neoh KH,Chen S,Tang Z,Lee PF,Dai M,Han RPS
MHCD4520 was used in Flow cytometry to report on the clinical value of a phenotypic circulating tumor cell (CTC)-based blood test for a preoperative prognostic assessment of tumor metastasis and overall survival (OS) of PDAC patients.
Thu Aug 01 00:00:00 EDT 2019
CTC phenotyping for a preoperative assessment of tumor metastasis and overall survival of pancreatic ductal adenocarcinoma patients.
EBioMedicine
Sun Y,Wu G,Cheng KS,Chen A,Neoh KH,Chen S,Tang Z,Lee PF,Dai M,Han RPS
MHCD4520 was used in Flow cytometry to report on the clinical value of a phenotypic circulating tumor cell (CTC)-based blood test for a preoperative prognostic assessment of tumor metastasis and overall survival (OS) of PDAC patients.
Thu Aug 01 00:00:00 EDT 2019
CTC phenotyping for a preoperative assessment of tumor metastasis and overall survival of pancreatic ductal adenocarcinoma patients.
EBioMedicine
Sun Y,Wu G,Cheng KS,Chen A,Neoh KH,Chen S,Tang Z,Lee PF,Dai M,Han RPS
MHCD4520 was used in Flow cytometry to report on the clinical value of a phenotypic circulating tumor cell (CTC)-based blood test for a preoperative prognostic assessment of tumor metastasis and overall survival (OS) of PDAC patients.
Thu Aug 01 00:00:00 EDT 2019
Single-cell mRNA cytometry via sequence-specific nanoparticle clustering and trapping.
Nature chemistry
Labib M,Mohamadi RM,Poudineh M,Ahmed SU,Ivanov I,Huang CL,Moosavi M,Sargent EH,Kelley SO
MHCD4520 was used in Immunocytochemistry-immunoflourescence to develop a method for cell analysis-single-cell mRNA cytometry-that enables the isolation of rare cells from whole blood as a function of target mRNA sequences.
Tue May 01 00:00:00 EDT 2018
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
Published figure using CD45 monoclonal antibody (Product # MHCD4520) in Immunohistochemistry
Fri Mar 29 00:00:00 EDT 2019
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss.
Nature communications
Quarta M,Cromie M,Chacon R,Blonigan J,Garcia V,Akimenko I,Hamer M,Paine P,Stok M,Shrager JB,Rando TA
Published figure using CD45 monoclonal antibody (Product # MHCD4520) in Flow Cytometry
Tue Jun 20 00:00:00 EDT 2017
Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking.
Nature nanotechnology
Poudineh M,Aldridge PM,Ahmed S,Green BJ,Kermanshah L,Nguyen V,Tu C,Mohamadi RM,Nam RK,Hansen A,Sridhar SS,Finelli A,Fleshner NE,Joshua AM,Sargent EH,Kelley SO
MHCD4520 was used in flow cytometry to investigate use of nanoparticle-mediated magnetic ranking for heterogeneous circulating tumour cells.
Wed Mar 01 00:00:00 EST 2017
An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy.
Nature biotechnology
Quarta M,Brett JO,DiMarco R,De Morree A,Boutet SC,Chacon R,Gibbons MC,Garcia VA,Su J,Shrager JB,Heilshorn S,Rando TA
MHCD4520 was used in flow cytometry to develop an artificial niche to maintain muscle stem cells in a potent and quiescent state
Fri Jul 01 00:00:00 EDT 2016
Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection.
Mucosal immunology
Yawata N,Selva KJ,Liu YC,Tan KP,Lee AW,Siak J,Lan W,Vania M,Arundhati A,Tong L,Li J,Mehta JS,Yawata M
MHCD4520 was used in flow cytometry to investigate the dynamics and characteristics of natural killer cell types in the human ocular mucosal surface in situ during infection with group D human adenoviruses.
Fri Jan 01 00:00:00 EST 2016
Deformability-based cell selection with downstream immunofluorescence analysis.
Integrative biology : quantitative biosciences from nano to macro
Shaw Bagnall J,Byun S,Miyamoto DT,Kang JH,Maheswaran S,Stott SL,Toner M,Manalis SR
MHCD4520 was used in immunocytochemistry to develop a cell sorting technique for use with a suspended microchannel resonator that measures the biophysical characteristics of a single cell
Mon May 16 00:00:00 EDT 2016
Deformability-based cell selection with downstream immunofluorescence analysis.
Integrative biology : quantitative biosciences from nano to macro
Shaw Bagnall J,Byun S,Miyamoto DT,Kang JH,Maheswaran S,Stott SL,Toner M,Manalis SR
MHCD4520 was used in immunocytochemistry to develop a cell sorting technique for use with a suspended microchannel resonator that measures the biophysical characteristics of a single cell
Mon May 16 00:00:00 EDT 2016
Deformability of Tumor Cells versus Blood Cells.
Scientific reports
Shaw Bagnall J,Byun S,Begum S,Miyamoto DT,Hecht VC,Maheswaran S,Stott SL,Toner M,Hynes RO,Manalis SR
Fri Dec 18 00:00:00 EST 2015