MA49A0 targets CD49a in FACS, IHC(F), IP, and WB applications and shows reactivity with Human samples.
The MA49A0 immunogen is human VLA-1 antigen.
MA49A0 detects CD49a which has a predicted molecular weight of approximately 128 kDa.
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
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Protein Aliases: CD49 antigen-like family member A; CD49a; integrin alpha 1; Integrin alpha-1; integrin, alpha 1; ITGA1; Laminin and collagen receptor; very late activation protein 1; VLA-1
Gene Aliases: CD49a; ITGA1; VLA1
UniProt ID: (Human) P56199
Entrez Gene ID: (Human) 3672