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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.
The CD5, a transmembrane protein, is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphoma are CD5-.
Analyte Specific Reagent
Separation of functional subsets of human T cells by a monoclonal antibody.
MHCD0504 was used in flow cytometry to characterize OKT4 positive T cells.
|Reinherz EL,Kung PC,Goldstein G,Schlossman SF||Proceedings of the National Academy of Sciences of the United States of America (76:4061)||1979|
CD5 antigen (p56-62), lymphocyte antigen T1/Leu-1, CD5 antigen p56-62
Signal transduction Cell communication Cell adhesion-mediated signaling Ligand-mediated signaling Immunity and defense T-cell mediated immunity Developmental processes Mesoderm development Hematopoiesis