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Invitrogen
CD52 Polyclonal Antibody
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FIGURE: 1 / 3
CD52 Antibody (PA5-103301) in IHC (P)
Immunohistochemistry analysis of CD52 in human prostate cancer and para-carcinoma tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with CD52 polyclonal antibody (Product # PA5-103301) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103301
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CD52(Accession P31358), corresponding to amino acid residues L5-I55.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CD52.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDw52; CDW52 antigen (CAMPATH-1 antigen); Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
Gene Aliases: CD52; CDW52; HE5
UniProt ID: (Human) P31358
Entrez Gene ID: (Human) 1043
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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