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Proteintech
CD6 Polyclonal Antibody
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Product Details
31998-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CD6 fusion protein Eg1401
Conjugate
Form
Liquid
Concentration
450 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: GLPSPAPSGQ HKNGTIPNMT LDLEERLGIR LVNGSSRCSG SVKVLLESWE PVCAAHWNRA ATEAVCKALN CGDSGKVTYL MPPTSELPPG ATSGNTSSAG NTTWARAPTE RCRGANWQFC KVQDQECSSD RRLVWVTCAE NQAVRLVDGS SRCAGRVEML EHGEWGTVCD DTWDLQDAHV VCKQLKCGWA VKALAGLHFT PGQGPIHRDQ VNCSGTEAYL WDCPGRPGDQ YCGHKEDAGV VCSEHQSWRL TGGIDSCEGQ VEVYFRGVWS TVCDSEWYPS EAKVLCRSLG CGSAVARPRG LPHSLDGRMY YSCKGQEPAL STCSWRFNNS NLCSQSRAAR VVCSGSQRHL NLSTSEVPSR VPVTIESSVP VSVKDKDSQG
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD6; CD6 antigen, Tp120; FLJ44171; T-cell differentiation antigen CD6
Gene Aliases: Cd6; OX52
UniProt ID: (Mouse) Q61003
Entrez Gene ID: (Mouse) 12511, (Rat) 25752
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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