|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||PBS with sucrose, 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 2 publications below|
R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.
CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
Analyte Specific Reagent
The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1.
MHCD62L04 was used in flow cytometry to study the role of CREB coactivator CRTC2 in hepatic lipid metabolism.
|Han J,Li E,Chen L,Zhang Y,Wei F,Liu J,Deng H,Wang Y||Nature (524:243)||2015|
A single dose of inactivated hepatitis A vaccine promotes HAV-specific memory cellular response similar to that induced by a natural infection.
MHCD62L04 was used in flow cytometry to evaluate the immune efficacy of a single-dose inactivated hepatitis A vaccination.
|Melgaço JG,Morgado LN,Santiago MA,Oliveira JM,Lewis-Ximenez LL,Hasselmann B,Cruz OG,Pinto MA,Vitral CL||Vaccine (33:3813)||2015|