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Invitrogen
CD64 Polyclonal Antibody
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FIGURE: 1 / 9
CD64 Antibody (PA5-102382) in ICC/IF
Immunocytochemistry analysis of CD64 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CD64 polyclonal antibody (Product # PA5-102382) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-102382
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FCGR1A(Accession P12314), corresponding to amino acid residues E244-L294.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FCGR1A.
Target Information
CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD64; CD64 antigen; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc receptor, IgG, high affinity I; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FcgRI; FcRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; High affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; IgG high affinity Fc receptor; RP11-196G18.2; unnamed protein product
Gene Aliases: AI323638; AV092959; CD64; CD64A; FCG1; FcgammaRI; FCGR1; FCGR1A; Fcgr1b; FCRI; IGFR1; IGGHAFC
UniProt ID: (Human) Q5QNW7, (Mouse) P26151
Entrez Gene ID: (Human) 2209, (Mouse) 14129, (Rat) 295279
antibody-dependent cellular cytotoxicity
positive regulation of type IIa hypersensitivity
positive regulation of type III hypersensitivity
immune system process
receptor-mediated endocytosis
phagocytosis, recognition
phagocytosis, engulfment
immune response
signal transduction
cell surface receptor signaling pathway
response to bacterium
antigen processing and presentation of exogenous antigen
positive regulation of tumor necrosis factor production
Fc-gamma receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
innate immune response
positive regulation of phagocytosis
regulation of immune response
positive regulation of phagocytosis, engulfment
response to estradiol
response to epinephrine
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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