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AbboMax

CD66a/c/e Monoclonal Antibody (ASL-32)

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Product Details

605-050

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL
-

Flow Cytometry (Flow)

0.5-5 µg/10^6 cells
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

ASL-32

Immunogen

A recombinant protein of human CD66

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive control: Human platelet lysate

Cellular location: Membrane.

Target Information

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. (PubMed: 16919437)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: antigen CD66; BGP; BGP-1; Biliary glycoprotein 1; biliary glycoprotein adhesion molecule; biliary glycoprotein I precursor; carcinoembronyic antigen; Carcinoembryonic antigen; carcinoembryonic antigen precursor; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 6; Carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66a antigen; CD66c; CD66e; CEA; CEA cell adhesion molecule 1; CEA cell adhesion molecule 5; CEA cell adhesion molecule 6; CEACAM1-3S; Cell adhesion molecule CEACAM1; Cell adhesion molecule CEACAM5; Cell adhesion molecule CEACAM6; Cluster of Differentiation 66c; Meconium antigen 100; Non-specific crossreacting antigen; nonspecific crossreacting antigen precursor; Normal cross-reacting antigen; ORF1; ORF2; unnamed protein product

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Gene Aliases: BGP; BGP1; BGPI; CD66c; CD66e; CEA; CEACAM1; CEACAM5; CEACAM6; CEAL; NCA; NCA-50/90

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UniProt ID: (Human) P13688, (Human) P06731, (Human) P40199

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Entrez Gene ID: (Human) 634, (Human) 1048, (Human) 4680

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Function(s)
actin binding protein binding calmodulin binding bile acid transmembrane transporter activity kinase binding protein phosphatase binding filamin binding identical protein binding protein homodimerization activity protein dimerization activity protein tyrosine kinase binding GPI anchor binding protein heterodimerization activity
Process(es)
apoptotic process cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules positive regulation of cell proliferation positive regulation of cell migration positive regulation of heterotypic cell-cell adhesion positive regulation of endothelial cell-matrix adhesion via fibronectin negative regulation of anoikis angiogenesis regulation of cell growth blood vessel development negative regulation of T cell mediated cytotoxicity regulation of immune system process negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target negative regulation of protein kinase activity signal transduction integrin-mediated signaling pathway regulation of endothelial cell migration bile acid and bile salt transport cell migration regulation of cell migration negative regulation of granulocyte differentiation negative regulation of interleukin-1 production cellular response to insulin stimulus common myeloid progenitor cell proliferation insulin receptor internalization granulocyte colony-stimulating factor signaling pathway regulation of epidermal growth factor receptor signaling pathway negative regulation of vascular permeability negative regulation of cytotoxic T cell degranulation wound healing, spreading of cells regulation of endothelial cell differentiation negative regulation of fatty acid biosynthetic process negative regulation of T cell receptor signaling pathway negative regulation of lipid biosynthetic process regulation of protein kinase B signaling regulation of blood vessel remodeling regulation of ERK1 and ERK2 cascade negative regulation of platelet aggregation cell-cell adhesion via plasma-membrane adhesion molecules insulin catabolic process regulation of homophilic cell adhesion regulation of sprouting angiogenesis negative regulation of hepatocyte proliferation positive regulation of vasculogenesis negative regulation of myotube differentiation homotypic cell-cell adhesion negative regulation of apoptotic process
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