NeoBiotechnologies

CD79a Recombinant Rabbit Monoclonal Antibody (IGA, 1688R)

Product Image Gallery

CD79a Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry/Immunofluorescence analysis of PFA-fixed Raji cells using CD79a Recombinant Monoclonal Antibody (Product # 973-RBM8-P1ABX) followed by goat anti-rabbit IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).

CD79a Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human tonsil using CD79a Recombinant Monoclonal Antibody (Product # 973-RBM8-P1ABX).

CD79a Antibody in Western Blot (WB) — Western Blot analysis of human Raji cell lysate using CD79a Recombinant Monoclonal Antibody (Product # 973-RBM8-P1ABX).

CD79a Antibody in Flow Cytometry (Flow) — Flow Cytometry analysis of Raji cells using CD79a Recombinant Monoclonal Antibody (Product # 973-RBM8-P1ABX) followed by Goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).

CD79a Antibody — SDS-PAGE Analyis Purified CD79a Recombinant Monoclonal Antibody (Product # 973-RBM8-P1ABX). Confirmation of Purity and Integrity of Antibody.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

Immunocytochemistry (ICC/IF)

1-2 µg/mL

Flow Cytometry (Flow)

1-2 µg/10^6 cells

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Recombinant Monoclonal

Type

Antibody

Clone

IGA, 1688R

Immunogen

A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Product Specific Information

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

Target Information

CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; Ig alpha; Ig-alpha; immunoglobulin-associated alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein

Gene Aliases: CD79A; Ig-alpha; IGA; Igalpha; Ly-54; Ly54; MB-1; MB1

UniProt ID: (Human) P11912, (Mouse) P11911

Entrez Gene ID: (Human) 973, (Mouse) 12518, (Rat) 100913063

Molecular Function: immunoglobulin receptor superfamily