Product References
Droplet-microfluidics-assisted sequencing of HIV proviruses and their integration sites in cells from people on antiretroviral therapy.
Nature biomedical engineering
Sun C,Liu L,Pérez L,Li X,Liu Y,Xu P,Boritz EA,Mullins JI,Abate AR
MHCD0828 was used in Flow cytometry/Cell sorting to show that full-length proviruses connected to their contiguous HIV-host DNA junctions can be assembled via a high-throughput microfluidic assay where droplet-based whole-genome amplification of HIV DNA in its native context is followed by a polymerase chain reaction (PCR) to tag droplets containing proviruses for sequencing.
Mon Aug 01 00:00:00 EDT 2022
Pilot trial of topical MTS‑01 application to reduce dermatitis in patients receiving chemoradiotherapy for stage I‑III carcinoma of the anal canal.
International journal of oncology
Citrin D,Valle L,Camphausen K,Cooley-Zgela T,Smart D,Yao M,Mitchell JB,Thompson W,Sereti I,Uldrick T
MHCD0828 was used in flow cytometry experiments to demonstrate that the MTS-01 topical application was tolerable with minimal toxicity.
Wed Jun 01 00:00:00 EDT 2022
A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires.
Frontiers in immunology
Ceglia V,Kelley EJ,Boyle AS,Zurawski S,Mead HL,Harms CE,Blanck JP,Flamar AL,Kirschman JH,Ogongo P,Ernst JD,Levy Y,Zurawski G,Altin JA
MHCD0828 was used in flow cytometry to show that clonotypes within each CET respond to the same epitope, and that protein antigens stimulate multiple CETs reactive to constituent peptides.
Fri Feb 04 00:00:00 EST 2022
Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines.
Frontiers in immunology
Ceglia V,Zurawski S,Montes M,Kroll M,Bouteau A,Wang Z,Ellis J,Igyártó BZ,Lévy Y,Zurawski G
MHCD0828 was used in Flow Cytometry to demonstrate that human CD40-CD40L antibody fused to antigens maintains highly agonistic activity and generates immune responses distinct from existing low agonist anti-CD40 targeting formats.
Thu Feb 24 00:00:00 EST 2022
Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines.
Frontiers in immunology
Ceglia V,Zurawski S,Montes M,Kroll M,Bouteau A,Wang Z,Ellis J,Igyártó BZ,Lévy Y,Zurawski G
MHCD0828 was used in Flow Cytometry to demonstrate that human CD40-CD40L antibody fused to antigens maintains highly agonistic activity and generates immune responses distinct from existing low agonist anti-CD40 targeting formats.
Thu Feb 24 00:00:00 EST 2022
Clonal replacement of tumor-specific T cells following PD-1 blockade.
Nature medicine
Yost KE,Satpathy AT,Wells DK,Qi Y,Wang C,Kageyama R,McNamara KL,Granja JM,Sarin KY,Brown RA,Gupta RK,Curtis C,Bucktrout SL,Davis MM,Chang ALS,Chang HY
MHCD0828 was used in Flow cytometry/Cell sorting to demonstrate that pre-existing tumor-specific T cells may have limited reinvigoration capacity, and that the T cell response to checkpoint blockade derives from a distinct repertoire of T cell clones that may have just recently entered the tumor.
Thu Aug 01 00:00:00 EDT 2019
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade.
Oncoimmunology
De Waele J,Marcq E,Van Audenaerde JR,Van Loenhout J,Deben C,Zwaenepoel K,Van de Kelft E,Van der Planken D,Menovsky T,Van den Bergh JM,Willemen Y,Pauwels P,Berneman ZN,Lardon F,Peeters M,Wouters A,Smits EL
MHCD0828 was used in Flow cytometry/Cell sorting to study the combination of poly(I:C) and PD-L1 blockade to invigorate the immune checkpoint inhibition response in glioblastoma.
Tue Jan 12 00:00:00 EST 2021
The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells.
Oncotarget
Willemen Y,Van den Bergh JM,Bonte SM,Anguille S,Heirman C,Stein BM,Goossens H,Kerre T,Thielemans K,Peeters M,Van Tendeloo VF,Smits EL,Berneman ZN
MHCD0828 was used in flow cytometry to assess receptor for hyaluronic acid-mediated motility specific dendritic cell responses
Tue Nov 08 00:00:00 EST 2016
Concomitant evaluation of PMA+ionomycin-induced kinase phosphorylation and cytokine production in T cell subsets by flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Crawford TQ,Jalbert E,Ndhlovu LC,Barbour JD
Published figure using CD8 monoclonal antibody (Product # MHCD0828) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo.
PLoS pathogens
Introini A,Vanpouille C,Lisco A,Grivel JC,Margolis L
MHCD0828TR was used in flow cytometry to study facilitation of HIV-1 transmission to cervico-vaginal tissue ex vivo by interleukin-7
Fri Feb 01 00:00:00 EST 2013
Establishment of a neonatal rhesus macaque model to study Mycobacterium tuberculosis infection.
Tuberculosis (Edinburgh, Scotland)
Cepeda M,Salas M,Folwarczny J,Leandro AC,Hodara VL,de la Garza MA,Dick EJ,Owston M,Armitige LY,Gauduin MC
MHCD0828 was used in flow cytometry to develop a newborn/infant model to study infection with Mycobacterium tuberculosis
Sun Dec 01 00:00:00 EST 2013
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
MHCD0828 was used in flow cytometry to develop and validate a novel system for high throughput quantitation of autophagy in primary human leukocytes.
Sun Apr 01 00:00:00 EDT 2012
A CD8α(-) subpopulation of macaque circulatory natural killer cells can mediate both antibody-dependent and antibody-independent cytotoxic activities.
Immunology
Vargas-Inchaustegui DA,Demberg T,Robert-Guroff M
MHCD0828 was used in flow cytometry to characterize different macaque NK cell subpopulations.
Tue Nov 01 00:00:00 EDT 2011
HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.
Journal of virology
Crawford TQ,Ndhlovu LC,Tan A,Carvidi A,Hecht FM,Sinclair E,Barbour JD
MHCD0828 was used in flow cytometry to elucidate relationships among MAPK pathway function, HIV-1-induced activation, and exhaustion markers in circulating CD8+ T cells
Thu Dec 01 00:00:00 EST 2011
Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
PloS one
Comin-Anduix B,Sazegar H,Chodon T,Matsunaga D,Jalil J,von Euw E,Escuin-Ordinas H,Balderas R,Chmielowski B,Gomez-Navarro J,Koya RC,Ribas A
MHCD0828 was used in flow cytometry to assess the effects on cell signaling networks upon blockade of cytotoxic T lymphocyte-associated antigen-4 in patients with metastatic melanoma
Wed Sep 15 00:00:00 EDT 2010