Immunogen sequence: KDSEIFTVNG ILGESVTFPV NIQEPRQVKI IAWTSKTSVA YVTPGDSETA PVVTVTHRNY YERIHALGPN YNLVISDLRM EDAGDYKADI NTQADPYTTT KRYNLQIYRR LGKPKITQSL MASVNSTCNV TLTCSVEKEE KNVTYNWSPL GEEGNVLQIF QTPEDQELTY TCTAQNPVSN NSDSISARQL CADIAMGFRT HHTG; Positive Samples: Jurkat, THP-1; Cellular Location: Cell membrane, Single-pass type I membrane protein
CD84 is expressed on mature B cells and on B cell lines, including pre B cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
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Protein Aliases: CD84; CD84 antigen (leukocyte antigen); Cell surface antigen MAX.3; Hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; SLAM family member 5
Gene Aliases: CD84; hCD84; LY9B; mCD84; SLAMF5
UniProt ID: (Human) Q9UIB8
Entrez Gene ID: (Human) 8832