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Invitrogen
CD94 Polyclonal Antibody
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FIGURE: 1 / 2
CD94 Antibody (PA5-102559) in ICC/IF
Immunofluorescent analysis of CD94 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CD94 polyclonal antibody (Product # PA5-102559) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-102559
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KLRD1(Accession Q13241), corresponding to amino acid residues S134-I179.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total KLRD1.
Target Information
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD94; CD94 antigen; CD94 antigen (located within the rat natural killer gene complex); Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; natural killer cell receptor; Natural killer cells antigen CD94; NK cell receptor; unnamed protein product
Gene Aliases: CD94; KLRD1
UniProt ID: (Human) Q13241, (Rat) O35778, (Mouse) O54707
Entrez Gene ID: (Human) 3824, (Rat) 25110, (Mouse) 16643
negative regulation of T cell mediated cytotoxicity
stimulatory C-type lectin receptor signaling pathway
natural killer cell mediated immunity
adaptive immune response
immune system process
cell surface receptor signaling pathway
regulation of natural killer cell activation
innate immune response
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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