|Tested species reactivity||Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 220-270 of human Leukocyte antigen CD97.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||3-5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-41590 detects Leukocyte Antigen CD97 in chimpanzee, mouse and human samples.
CD97 is a monomeric glycoprotein belonging to G-protein coupled receptor 2 family and having a seven-span transmembrane region homologous to the secretin receptor super family. It is usually induced on the surface of activated leukocytes and has four tandem EGF-like domains two of them have calcium binding sites and a single RGD motif and several potential N and O glycosylation sites. It is known to act as a receptor that is not only involved in adhesion but also takes part in signaling processes early after leukocyte activation and also has a cellular ligand CD55, DAF. Over expression of this protein may sometimes lead to gastrointestinal carcinomas. CD97 an epidermal growth factor (EGF)-TM7 receptor is expressed on smooth muscle cells and other cells of the immune system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.