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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD97 Antibodies

          Invitrogen

          CD97 Polyclonal Antibody

          View all (35) CD97 antibodies

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          Cite CD97 Polyclonal Antibody

          • Antibody Testing Data (3)
          CD97 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          CD97 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          CD97 Antibody (PA1-41590) in IHC (P)

          Immunohistochemical analysis of CD97 in human spleen. Samples were incubated in CD97 polyclonal antibody (Product # PA1-41590) using a dilution of 10 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD97 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CD97 Antibody in Western Blot (WB)
          CD97 Antibody in Western Blot (WB)
          CD97 Polyclonal Antibody

          Product Details

          PA1-41590

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          3-5 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Non-human primate

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A portion of amino acids 220-270 of human Leukocyte Antigen CD97.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 0.2% gelatin

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2076172

          Product Specific Information

          PA1-41590 detects Leukocyte Antigen CD97 in chimpanzee, mouse and human samples.

          Target Information

          CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Adhesion G protein-coupled receptor E5; CD97; CD97 antigen; CD97 molecule; EGF-TM7 receptor; Leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation

          View more View less

          Gene Aliases: AA409984; ADGRE5; CD97; TM7LN1

          View more View less

          UniProt ID: (Human) P48960, (Mouse) Q9Z0M6

          View more View less

          Entrez Gene ID: (Human) 976, (Mouse) 26364

          View more View less

          Function(s)
          transmembrane signaling receptor activity G-protein coupled receptor activity calcium ion binding protein binding signal transducer activity G-protein coupled receptor
          Process(es)
          movement of cell or subcellular component inflammatory response immune response cell adhesion cell surface receptor signaling pathway G-protein coupled receptor signaling pathway cell-cell signaling signal transduction positive regulation of synapse assembly
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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