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Proteintech
CD98 Polyclonal Antibody
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Product Details
15193-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CD98/SLC3A2 Fusion Protein Ag7280 (269-630 aa encoded by BC001061)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KDDVAQTDL LQIDPNFGSK EDFDSLLQSA KKKSIRVILD LTPNYRGENS WFSTQVDTVA TKVKDALEFW LQAGVDGFQV RDIENLKDAS SFLAEWQNIT KGFSEDRLLI AGTNSSDLQQ ILSLLESNKD LLLTSSYLSD SGSTGEHTKS LVTQYLNATG NRWCSWSLSQ ARLLTSFLPA QLLRLYQLML FTLPGTPVFS YGDEIGLDAA ALPGQPMEAP VMLWDESSFP DIPGAVSANM TVKGQSEDPG SLLSLFRRLS DQRSKERSLL HGDFHAFSAG PGLFSYIRHW DQNERFLVVL NFGDVGLSAG LQASDLPASA SLPAKADLLL STQPGREEGS PLELERLKLE PHEGLLLRFP YAA (269-630 aa encoded by BC001061)
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 4F2 antigen heavy chain; 4F2 cell-surface antigen; 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; Amino acid transporter heavy chain SLC3A2; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; CD98; CD98 antigen; CD98 heavy chain; lymphocyte activation antigen; Lymphocyte activation antigen 4F2 large subunit; monoclonal antibody 44D7; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; Solute carrier family 3 member 2; type II transmembrane protein; unnamed protein product
Gene Aliases: 4F2; 4F2HC; 4T2HC; AI314110; CD98; CD98HC; Ly-10; Ly-m10; Ly10; MDU1; Mgp-2hc; NACAE; SLC3A2
UniProt ID: (Human) P08195, (Mouse) P10852
Entrez Gene ID: (Human) 6520, (Mouse) 17254
virus receptor activity
RNA binding
double-stranded RNA binding
protein binding
aromatic amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-alanine transmembrane transporter activity
L-leucine transmembrane transporter activity
protein homodimerization activity
cadherin binding
protein heterodimerization activity
exogenous protein binding
catalytic activity
cation binding
poly(A) RNA binding
amino acid transmembrane transport
carbohydrate metabolic process
transport
amino acid transport
neutral amino acid transport
response to exogenous dsRNA
leucine import
calcium ion transport
isoleucine transport
leucine transport
methionine transport
phenylalanine transport
proline transport
tryptophan transport
tyrosine transport
valine transport
viral entry into host cell
thyroid hormone transport
L-histidine transport
L-leucine import across plasma membrane
L-alanine import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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