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Invitrogen
CDA Polyclonal Antibody
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Product Details
PA5-27478
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CDA. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Amount
71 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431, HeLa, mouse kidney.
Predicted reactivity: Mouse (86%), Rat (86%), Pig (87%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytidine aminohydrolase; Cytidine deaminase; cytosine nucleoside deaminase; EC 3.5.4.5; hscd; small cytidine deaminase
Gene Aliases: 2210401N16Rik; CDA; CDD
UniProt ID: (Human) P32320, (Mouse) P56389
Entrez Gene ID: (Human) 978, (Mouse) 72269
pyrimidine-containing compound salvage
cytosine metabolic process
UMP salvage
response to cycloheximide
nucleobase-containing small molecule metabolic process
cellular response to external biotic stimulus
pyrimidine-containing compound metabolic process
carbohydrate derivative metabolic process
cytidine deamination
negative regulation of cell growth
negative regulation of nucleotide metabolic process
protein homotetramerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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