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          • Primary Antibodies ›
          • Cdc25A Antibodies

          Proteintech

          CDC25A Polyclonal Antibody

          36 References
          View all (37) Cdc25A antibodies

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          Cite CDC25A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (10)
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          CDC25A Antibody (55031-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 55031-1-AP ( CDC25A Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDC25A Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          CDC25A Antibody in Western Blot (WB)
          CDC25A Antibody in Western Blot (WB)
          CDC25A Antibody in Immunoprecipitation (IP)

          Product Details

          55031-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 25 publications 25 publications

          Immunohistochemistry (IHC)

          -
          View 5 publications 5 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 5 publications 5 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.53 mg/mL

          Amount

          79.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M sodium bicarbonate/0.1M glycine, pH 7.3, with 50% glycerol, 0.1M glycine

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          The antibody is specific to CDC25A.

          Target Information

          CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CDC25 homolog A; CDC25A2; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1; phosphatase; putative; unnamed protein product

          View more View less

          Gene Aliases: CDC25A; CDC25A2; Cdc25m3; D9Ertd393e

          View more View less

          UniProt ID: (Human) P30304, (Mouse) P48964

          View more View less

          Entrez Gene ID: (Human) 993, (Mouse) 12530

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding hydrolase activity protein kinase binding chaperone binding protein phosphatase
          Process(es)
          regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle nuclear envelope organization mitotic nuclear envelope disassembly cell proliferation response to radiation positive regulation of G2/M transition of mitotic cell cycle positive regulation of DNA replication cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition mitotic M phase protein dephosphorylation cell cycle mitotic nuclear division dephosphorylation cellular response to UV
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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