Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
In Jurkat cell, this antibody recognized 2 bands: 60 kDa (isoform 2, CDC25B2) and 70 kDa (isoform 4 of CDC25B).
Immunogen sequence: MEVPQPEPA PGSALSPAGV CGGAQRPGHL PGLLLGSHGL LGSPVRAAAS SPVTTLTQTM HDLAGLGSET PKSQVGTLLF RSRSRLTHLS LSRRASESSL SSESSESSDA GLCMDSPSPM DPHMAEQTFE QAIQAASRII RNEQFAIRRF QSMPVRLLGH SPVLRNITNS QAPDGRRKSE AGSGAASSSG EDKENDGFVF KMPWKPTHPS STHALAEWAS RREAFAQRPS SAPDLMCLSP DRKMEVEELS PLALGRFSLT PAEGDTEEDD GFVDILESDL KDDDAVPPGM ESLISAPLVK T (1-300 aa encoded by BC006395)
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support