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QED Bioscience
CDC25a Polyclonal Antibody
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FIGURE: 1 / 2
CDC25a Antibody (13022-100UG) in WB
Detection of human CDC25a by western blot. Samples: Nuclear extract (50 µg) from HeLa and HEK293T cells. Antibody: Affinity purified rabbit anti-CDC25a antibody 13022 (lot 13022-2) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
13022-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide representing a portion of the protein encoded by exon 7 (LocusLink ID 993).
Conjugate
Form
Liquid
Concentration
0.5-1.0 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
2-8°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC25 homolog A; CDC25A2; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1; phosphatase; putative; unnamed protein product
Gene Aliases: CDC25A; CDC25A2
UniProt ID: (Human) P30304
Entrez Gene ID: (Human) 993
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
nuclear envelope organization
mitotic nuclear envelope disassembly
cell proliferation
response to radiation
positive regulation of G2/M transition of mitotic cell cycle
positive regulation of DNA replication
cell division
positive regulation of G2/MI transition of meiotic cell cycle
positive regulation of cell cycle G2/M phase transition
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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