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Product Details
BS-4295R
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human CDC40, amino acids 481-579. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; hPRP17; pre-mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17 homolog
Gene Aliases: 1200003H23Rik; CDC40; EHB3; PRP17; PRPF17
UniProt ID: (Human) O60508, (Mouse) Q9DC48
Entrez Gene ID: (Human) 51362, (Mouse) 71713, (Rat) 361859
Molecular Function:
RNA metabolism protein
RNA processing factor
RNA splicing factor
nucleic acid metabolism protein
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