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Antibody detects endogenous levels of total CDCA7.
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-Myc target JPO1; Cell division cycle-associated protein 7; Protein JPO1
Gene Aliases: 2310021G01Rik; AU044109; CDCA7; ICF3; JPO1
UniProt ID: (Human) Q9BWT1, (Rat) Q4KM91, (Mouse) Q9D0M2
Entrez Gene ID: (Human) 83879, (Rat) 311742, (Mouse) 66953
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