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Immunogen sequence: PKFRSDISEE LANVFYEDSD NESFCGFSES EVQDVLDHCG FLQKPRPDVT NELAGIFHAD SDDESFCGFS ESEIQDGM
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 34%.
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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