In direct ELISAs, approximately 25% cross-reactivity with recombinant human CDCP1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
CDCP1 is a transmembrane protein containing three extracellular CUB domains. It is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. CDCP1 is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Protein Aliases: CD318; CUB domain-containing protein 1; gp140; Membrane glycoprotein gp140; Transmembrane and associated with src kinases
Gene Aliases: 9030022E12Rik; AA409659; Cdcp1; E030027H19Rik
UniProt ID: (Mouse) Q5U462
Entrez Gene ID: (Mouse) 109332