This antibody has specificity for Mouse Cadherin-17/LI-cadherin.
CDH17 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BILL-cadherin; Cadherin; Cadherin-17; FLJ26931; LI-cadherin; Liver-intestine cadherin; MGC138218; MGC142024; P130
Gene Aliases: Cdh17; HPT-1; HPT-1/LI
UniProt ID: (Mouse) Q9R100
Entrez Gene ID: (Mouse) 12557
Molecular Function: cadherin