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Proteintech
CDH23 Polyclonal Antibody
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Product Details
13496-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDH23 Fusion Protein Ag4322 (1-352 aa encoded by BC032581)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGRHVATSC HVAWLLVLIS GCWGQVNRLP FFTNHFFDTY LLISEDTPVG SSVTQLLAQD MDNDPLVFGV SGEEASRFFA VEPDTGVVWL RQPLDRETKS EFTVEFSVSD HQGVITRKVN IQVGDVNDNA PTFHNQPYSV RIPENTPVGT PIFIVNATDP DLGAGGSVLY SFQPPSQFFA IDSARGIVTV IRELDYETTQ AYQLTVNATD QDKTRPLSTL ANLAIIITDV QDMDPIFINL PYSTNIYEHS PPGTTVRIIT AIDQDKGRPR GIGYTIVSGN TNSIFALDYI SGVLTLNGLL DRENPLYSHG FILTVKGTEL NDDRTPSDAT VTTTFNILVI DINDNAPEFN SSE (1-352 aa encoded by BC032581)
Target Information
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: age related hearing loss 1; bobby; bustling; Cadherin; cadherin 23; cadherin 23 (otocadherin); cadherin related 23; Cadherin-23; cadherin-like 23; cadherin-related family member 23; DFNB12; DKFZp434P2350; FLJ00233; FLJ36499; MGC102761; modifier of deaf waddler; Otocadherin; OTTHUMP00000044780; USH1H; waltzer; Waltzing
Gene Aliases: 4930542A03Rik; ahl; ahl1; bob; bus; CDH23; CDHR23; KIAA1774; KIAA1812; mdfw; nmf112; nmf181; nmf252; sals; UNQ1894/PRO4340; USH1D; v; W
UniProt ID: (Human) Q6UWW1, (Mouse) Q99PF4, (Rat) P58365
Entrez Gene ID: (Human) 64072, (Mouse) 22295, (Rat) 114102
calcium ion transport
homophilic cell adhesion via plasma membrane adhesion molecules
visual perception
sensory perception of sound
locomotory behavior
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
photoreceptor cell maintenance
response to stimulus
sensory perception of light stimulus
equilibrioception
regulation of cytosolic calcium ion concentration
inner ear receptor stereocilium organization
cell adhesion
adult locomotory behavior
inner ear morphogenesis
auditory receptor cell differentiation
post-embryonic organ morphogenesis
inner ear development
righting reflex
auditory receptor cell stereocilium organization
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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