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Immunogen sequence: QAQYCSVNKD IFEVEENTNV TEPLVDIHVP EGQEVTLGAL STPFAFRIQG NQLFLNVTPD YEEKSLLEAQ LLCQSGGTLV TQLRVFVSVL DVNDNAPEFP FKTKEIRVEE DTKVNSTVIP ETQLQAEDRD KDDILFYTLQ EMTAGASDYF SLVSVNRPAL RLDRPLDFYE RPNMTFWLLV RDTPGENVEP SHTAT; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein
This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: Cadherin; Cadherin-related family member 5; GP100; Mu-protocadherin; mucin and cadherin like; mucin and cadherin-like protein; mucin-like protocadherin
Gene Aliases: 1810074H01Rik; AI481143; Cdhr5; Mucdhl; Mupcdh
UniProt ID: (Rat) Q9JIK1, (Mouse) Q8VHF2
Entrez Gene ID: (Rat) 171554, (Mouse) 72040
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