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Bethyl Laboratories
CDK11 Polyclonal Antibody
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Product Details
IHC-00035
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 730 and the C-terminus (residue 780) of human Cell Division Cycle 2-like 2.
Conjugate
Form
Liquid
Concentration
0.50 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda and Orangutan
Target Information
CDK11 is a member of the cyclin-dependent kinase 11 family which is known to be essential for eukaryotic cell cycle control and it is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. CDK11 is a negative regulator of normal cell cycle progression and Its expression is regulated during murine embryogenesis, and its activity is coordinately regulated with that of p34 (cdc2) during the cell cycle. CDK11 gene may harbor 1 or more tumor suppressor genes that affected by chromosome 1p36 modifications in neuroblastoma. CDK11 could be cleaved by caspases and was demonstrated to play roles in cell apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC-related protein kinase p58; cell division cycle 2-like 1 (PITSLRE proteins); cell division cycle 2-like 2 (PITSLRE proteins); Cell division cycle 2-like protein kinase 1; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cell division protein kinase 11B; CLK-1; Cyclin-dependent kinase 11A; Cyclin-dependent kinase 11B; Galactosyltransferase-associated protein kinase p58/GTA; GR specific protein kinase; p58 CLK-1; PITSLRE B; PITSLRE serine/threonine-protein kinase CDC2L1; PITSLRE serine/threonine-protein kinase CDC2L2; unnamed protein product
Gene Aliases: CDC2L1; CDC2L2; CDC2L3; CDK11; CDK11-p110; CDK11-p46; CDK11-p58; CDK11A; CDK11B; CLK-1; p58; p58CDC2L1; p58CLK-1; p58GTA; PITSLRE; PITSLREA; PITSLREB; PK58
UniProt ID: (Human) Q9UQ88, (Human) P21127
Entrez Gene ID: (Human) 728642, (Human) 984
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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