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Immunogen sequence: MDQYCILGRI GEGAHGIVFK AKHVETGEIV ALKKVALRRL EDGFPNQALR EIKALQEMED NQYVVQLKAV FPHGGGFVLA FEFMLSDLAE VVRHAQRPLA QAQVKSYLQM LLKGVAFCHA NNIVHRDLKP ANLLISASGQ LKIADFGLAR VFSPDGSRLY THQVATRSVG CIMGELLNGS PLFPGKNDIE QLCYVLRILG TPNPQVWPEL TELPDYNKIS FKEQVPMPLE EVLPDVSPQA LDLLGQFLLY PPHQRIAASK LPCLPIHLSC RFLSV; Positive Samples: HeLa, U-87MG, HepG2, Mouse heart, Mouse eye; Cellular Location: Cell projection, Cytoplasm, Nucleus, cilium
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Protein Aliases: CAK-kinase p42; CDK-activating kinase p42; CDK-related protein kinase PNQLARE; cell cycle related kinase; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin-dependent kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42
Gene Aliases: 4932702G04Rik; AU019450; AW558027; CCRK; CDCH; CDK20; P42; PNQALRE; PNQLARE
UniProt ID: (Human) Q8IZL9, (Mouse) Q9JHU3
Entrez Gene ID: (Human) 23552, (Mouse) 105278
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