Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
Positive test controls include: 293T. The target is usually found in the following locations: Cell junction, Cell membrane, Cell projection, Cytoplasm, Nucleus, Perikaryon, Peripheral membrane protein, growth cone, lamellipodium, postsynaptic cell membrane, postsynaptic density, synapse.
Immunogen sequence: PDVLFGAKLY STSIDMWSAG CIFAELANAG RPLFPGNDVD DQLKRIFRLL GTPTEEQWPS MTKLPDYKPY PMYPATTSLV NVVPKLNATG RDLLQNLLKC NPVQRISAEE ALQHPYFSDF
CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDK5-SV; Cell division protein kinase 5; CR6 protein kinase; Cyclin-dependent kinase 5; Cyclin-dependent-like kinase 5; protein kinase CDK5 splicing; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Aliases: AW048668; CDK5; CDKN5; Crk6; LIS7; PSSALRE
UniProt ID: (Human) Q00535, (Mouse) P49615, (Rat) Q03114
Entrez Gene ID: (Human) 1020, (Mouse) 12568, (Rat) 140908
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