PA5-28795 targets CDK5 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-28795 immunogen is synthetic peptide corresponding to a region within amino acids 229 and 292 of Human CDK5.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
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Protein Aliases: Cell division protein kinase 5; CR6 protein kinase; CRK6; cyclin-dependent kinase 5; Cyclin-dependent-like kinase 5; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Aliases: AW048668; CDK5; CDKN5; Crk6; LIS7; PSSALRE