The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
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Protein Aliases: CDK5 activator 2; Cyclin-dependent kinase 5 activator 2; cyclin-dependent kinase 5 activator isoform p39i; Cyclin-dependent kinase 5 regulatory subunit 2; cyclin-dependent kinase 5, regulatory subunit 2 (p39); neuronal CDK5 activator isoform; p39; p39I
Gene Aliases: B230310J22Rik; CDK5R2; NCK5AI; P39; p39nck5ai; RGD1562530
Molecular Function: kinase activator