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| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human CDKN3, amino acids 51-150. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cdk-associated protein phosphatase; CDK2-associated dual specificity phosphatase; CDK2-associated dual-specificity phosphatase; CDK2-associated dual-specificity phosphatase {ECO:0000250|UniProtKB:Q16667}; cdkn3; cdkn3 {ECO:0000312|EMBL:AAI67026.1, ECO:0000312|RGD:1307781}; cyclin-dependent kinase inhibitor; Cyclin-dependent kinase inhibitor 3; cyclin-dependent kinase inhibitor 3 {ECO:0000250|UniProtKB:Q16667}; cyclin-dependent kinase interacting protein 2; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; kinase associated phosphatase; Kinase-associated phosphatase; kinase-associated phosphatase {ECO:0000250|UniProtKB:Q16667}
Gene Aliases: 2410006H10Rik; CDI1; CDKN3; CIP2; KAP; KAP1
UniProt ID: (Human) Q16667, (Mouse) Q810P3, (Rat) B2RZ50
Entrez Gene ID: (Human) 1033, (Mouse) 72391, (Rat) 289993
Molecular Function:
protein phosphatase
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