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CDO1 Polyclonal Antibody
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Product Details
BS-5808R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CDO1, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart. CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDO; CDO-I; CDO1; CDOI; cysteine dioxygenase 1, cytosolic; Cysteine dioxygenase type 1; Cysteine dioxygenase type I; cysteine dioxygenase, type I; cytosolic cysteine dioxygenase 1; unnamed protein product
Gene Aliases: 1300002L19Rik; Cdo; CDO-I; CDO1; D18Ucla3
UniProt ID: (Human) Q16878, (Rat) P21816, (Mouse) P60334
Entrez Gene ID: (Human) 1036, (Rat) 81718, (Mouse) 12583
iron ion binding
ferrous iron binding
zinc ion binding
nickel cation binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
cysteine dioxygenase activity
metal ion binding
dioxygenase activity
oxidoreductase
oxygenase
metabolite interconversion enzyme
sulfur amino acid biosynthetic process
cysteine metabolic process
inflammatory response
lactation
L-cysteine catabolic process
response to glucagon
taurine biosynthetic process
response to amino acid
response to ethanol
response to glucocorticoid
response to cAMP
response to azide
response to organonitrogen compound
L-cysteine metabolic process
oxidation-reduction process
L-cysteine catabolic process to taurine
taurine metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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