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Invitrogen
CDO1 Polyclonal Antibody
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Product Details
PA5-119065
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein Cysteine Dioxygenase I. The antigen corresponds to amino acid range 1-200 of the target protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart. CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDO; CDO-I; CDO1; CDOI; cysteine dioxygenase 1, cytosolic; Cysteine dioxygenase type 1; Cysteine dioxygenase type I; cysteine dioxygenase, type I; cytosolic cysteine dioxygenase 1; unnamed protein product
Gene Aliases: CDO-I; CDO1
UniProt ID: (Human) Q16878, (Rat) P21816
Entrez Gene ID: (Human) 1036, (Pig) 100312964, (Rat) 81718
iron ion binding
ferrous iron binding
zinc ion binding
nickel cation binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
cysteine dioxygenase activity
metal ion binding
dioxygenase activity
oxidoreductase
oxygenase
metabolite interconversion enzyme
sulfur amino acid biosynthetic process
cysteine metabolic process
inflammatory response
lactation
L-cysteine catabolic process
response to glucagon
taurine biosynthetic process
response to amino acid
response to ethanol
response to glucocorticoid
response to cAMP
response to azide
response to organonitrogen compound
L-cysteine metabolic process
oxidation-reduction process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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