Immunogen sequence: MYVSYLLDKD VSMYPSSVRH SGGLNLAPQN FVSPPQYPDY GGYHVAAAAA AAANLDSAQS PGPSWPAAYG APLREDWNGY APGGAAAAAN AVAHGLNGGS; Positive Samples: 293T, MCF7, Mouse small intestine, Mouse thymus, Rat small intestine; Cellular Location: Nucleus
CDX2 is a member of caudal type homeo box family of transcription factor. CDX-2 is a permissive factor that influences basal CaBP expression in enterocytes; HNF-1alpha; modulates CaBP gene expression during cellular differentiation. CDX2, but not CDX1, interacts with the MUC2 promoter and activates MUC2 transcription, and plays an important role in the differentiation of goblet cells.
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Protein Aliases: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: Cdx-2; CDX-3; CDX2; CDX2/AS; CDX3