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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CDY2B Antibodies

          Invitrogen

          CDY2B Polyclonal Antibody

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          Cite CDY2B Polyclonal Antibody

          • Antibody Testing Data (1)
          CDY2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CDY2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CDY2B Antibody (PA5-140322) in IHC (P)

          Immunohistochemical analysis of CDY2B in human testis using CDY2B Polyclonal Antibody (Product # PA5-140322) shows strong nuclear positivity in cells in seminiferous ducts. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CDY2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDY2B Polyclonal Antibody

          Product Details

          PA5-140322

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CDY2B. Recombinant protein control fragment (Product #RP-109109).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2927324

          Product Specific Information

          Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

          Immunogen sequence: RQTEKQKKLT WTTTSRIFSN NARRRTSRST KANYSKNSP

          Highest antigen sequence indentity to the following orthologs: Mouse - 38%, Rat - 41%.

          Target Information

          CDY2B encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: chromodomain protein, Y chromosome, 2 related; Testis-specific chromodomain protein Y 2; testis-specific chromodomain protein Y protein 2 related; Y chromosome chromodomain protein 2B

          View more View less

          Gene Aliases: CDY; CDY2; CDY2A; CDY2B

          View more View less

          UniProt ID: (Human) Q9Y6F7

          View more View less

          Entrez Gene ID: (Human) 203611

          View more View less

          Function(s)
          histone acetyltransferase activity
          Process(es)
          spermatogenesis histone acetylation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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