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Proteintech
CDYL Polyclonal Antibody
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Product Details
17763-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDYL Fusion Protein Ag12143 (1-362 aa encoded by BC108725)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASEELYEV ERIVDKRKNK KGKTEYLVRW KGYDSEDDTW EPEQHLVNCE EYIHDFNRRH TEKQKESTLT RTNRTSPNNA RKQISRSTNS NFSKTSPKAL VIGKDHESKN SQLFAASQKF RKNTAPSLSS RKNMDLAKSG IKILVPKSPV KSRTAVDGFQ SESPEKLDPV EQGQEDTVAP EVAAEKPVGA LLGPGAERAR MGSRPRIHPL VPQVPGPVTA AMATGLAVNG KGTSPFMDAL TANGTTNIQT SVTGVTASKR KFIDDRRDQP FDKRLRFSVR QTESAYRYRD IVVRKQDGFT HILLSTKSSE NNSLNPEVMR EVQSALSTAA ADDSKLVLLS AVGSVFCCGL DFIYFIRRLT DDR (1-362 aa encoded by BC108725)
Target Information
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CDY-like; CDY-like, autosomal; chromodomain protein, Y chromosome-like; chromodomain protein, Y-like; Chromodomain Y-like protein; Crotonyl-CoA hydratase; DKFZp586C1622; MGC131936; Putative histone acetyltransferase Cdyl; Putative tubulin acetyltransferase Cdyl; testis-specific chromodomain Y-like protein; unnamed protein product
Gene Aliases: AI325931; CDYL; CDYL1
UniProt ID: (Human) Q9Y232, (Rat) Q6AYK9, (Mouse) Q9WTK2
Entrez Gene ID: (Human) 9425, (Rat) 361237, (Mouse) 12593
chromatin binding
transcription corepressor activity
protein binding
lyase activity
protein binding, bridging
identical protein binding
crotonyl-CoA hydratase activity
histone acetyltransferase activity
methylated histone binding
catalytic activity
transferase activity
transferase activity, transferring acyl groups
spermatogenesis
spermatid development
cell differentiation
negative regulation of transcription, DNA-templated
random inactivation of X chromosome
negative regulation of peptidyl-lysine crotonylation
transcription, DNA-templated
regulation of transcription, DNA-templated
histone acetylation
negative regulation of nucleic acid-templated transcription
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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