Positive Control: Jurkat, Raji, NCI-H929
Predicted reactivity: Human (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CEACAM7 is a CEA-related cell adhesion molecule 7 that belongs to the carcinoembryonic antigen (CEA) family. CEACAM7 encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BGP7; Carcinoembryonic antigen CGM2; carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen-related cell adhesion molecule 7
Gene Aliases: CEACAM7; CGM2
UniProt ID: (Human) Q14002
Entrez Gene ID: (Human) 1087
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein immunoglobulin receptor superfamily kinase membrane-bound signaling molecule protein kinase receptor signaling molecule transferase