Caboxyl Ester Lipase (CEL), also known as Bile Salt-Activated Lipase, catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). It also has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAL; Bile salt-activated lipase; bile salt-dependent lipase, oncofetal isoform; Bile salt-stimulated lipase; BSSL; bucelipase; carboxyl ester hydrolase; Carboxyl ester lipase; carboxyl ester lipase (bile salt-stimulated lipase); Cholesterol esterase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; Pancreatic lysophospholipase; Sterol esterase
Gene Aliases: 1810036E18Rik; BAL; BSDL; BSSL; CEase; Cel; CELL; FAP; FAPP; Lip1; LIPA; MODY8
UniProt ID: (Mouse) Q64285
Molecular Function: cell adhesion molecule