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CELSR2 Antibody (PA5-141150) in ICC/IF
Immunocytochemistry analysis of Cadherin EGF LAG seven-pass G-type receptor 2 in D3 (Murine Embryonic Stem Cell Line). Samples were incubated in Cadherin EGF LAG seven-pass G-type receptor 2 Polyclonal antibody (Product # PA5-141150) followed by goat anti-rabbit IgG (H+L) alexa555 conjugated (red) secondary antibody.
Product Details
PA5-141150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within Human Cadherin EGF LAG seven-pass G-type receptor 2 aa 21-70/2,923.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2932601
Target Information
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adhesion G protein-coupled receptor C2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; Epidermal growth factor-like protein 2; Flamingo homolog; Flamingo homolog 3; FLJ34118; FLJ42737; FLJ45143; FLJ45845; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3
Gene Aliases: ADGRC2; CDHF10; CELSR2; EGFL2; flamingo; Flamingo1; KIAA0279; MEGF3; mfmi1; mKIAA0279
UniProt ID: (Human) Q9HCU4, (Mouse) Q9R0M0
Entrez Gene ID: (Human) 1952, (Mouse) 53883
regulation of transcription, DNA-templated
homophilic cell adhesion via plasma membrane adhesion molecules
G-protein coupled receptor signaling pathway
spermatogenesis
Wnt signaling pathway
neural plate anterior/posterior regionalization
regulation of cell-cell adhesion
dendrite morphogenesis
Wnt signaling pathway, planar cell polarity pathway
neuron migration
cilium movement
cell adhesion
signal transduction
cell surface receptor signaling pathway
multicellular organism development
ventricular system development
regulation of protein localization
cerebrospinal fluid secretion
cilium assembly
Performance Guarantee
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