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PA1-4315 detects the SHPRH protein in mouse samples.
PA1-4315 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~200 kDa protein representing SHPRH in mouse brain lysate.
PA1-4315 immunizing peptide corresponds to amino acid residues 515-535 of the mouse SHPRH protein. There is 95% sequence identity to rat, and 90% sequence identity to human.
A novel gene containing SNF2, PHD-finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus suggests a role in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2610103K11Rik; AA450458; AU024614; BC006883; CENP-I; Centromere protein I; D230017O13Rik; E130018M05; Follicle-stimulating hormone primary response protein; FSH primary response protein 1; Mis6
Gene Aliases: CENP-I; Cenpi; Fshprh1
UniProt ID: (Mouse) Q8K1K4
Entrez Gene ID: (Mouse) 102920
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