Peptide sequence: SFKKILQRAL KNVTVSFRET EENAVWIRIA WGTQYTKPNQ YKPTYVVYYS
Sequence homology: Cow: 86%; Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 79%
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPN is an additional factor required for centromere assembly.
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Protein Aliases: CENP-N; Centromere protein N; FLJ13607; FLJ22660; Interphase centromere complex protein 32
Gene Aliases: BM-309; BM039; C16orf60; CENP-N; CENPN; ICEN32
UniProt ID: (Human) Q96H22
Entrez Gene ID: (Human) 55839